NFKBIB anticorps (AA 306-356)

N° du produit ABIN7451814

Cet anticorps anti-NFKBIB est un anticorps Lapin Polyclonal détectant NFKBIB dans WB et IP. Adapté pour Humain.

Aperçu rapide pour NFKBIB anticorps (AA 306-356) (ABIN7451814)

Antigène: NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFKBIB est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-NFKBIB anticorps

Épitope: AA 306-356

Fonction: Rabbit anti-I kappa B-beta Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 306 and 356

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur NFKBIB

Antigène: NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))

Autre désignation: I kappa B-beta

Sujet: Background: Activity of the transcription factor NF-kappa B is regulated by inhibitor proteins that interact with NF-kappa B and inhibit their DNA binding activity. These inhibitor proteins are members of the I kappa B family of proteins and include I kappa B-beta, I kappa B-delta/NF-kappa B2/p100, I kappa B-gamma/NF-kappa Bp105, I kappa B-epsilon, I kappa B-zeta, and Bcl3. Association with I kappa B proteins sequesters NF-kappa B in the cytoplasm to regulate its activity. The Phosphorylation of I kappa B by the I kappa B kinase complex (IKK) results in the ubiquitination and degradation of I kappa B and the release and translocation of NF-kappa B to the nucleus.

ID gène: 4793

NCBI Accession: NP_002494

UniProt: Q15653

Pathways: Signalisation NF-kappaB, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades